Cardiac Involvement in Thyroid Hormone Resistance
نویسندگان
چکیده
منابع مشابه
[Thyroid hormone resistance syndromes].
Thyroid hormone resistance syndromes are a group of genetic conditions characterized by decreased tissue sensitivity to thyroid hormones. Three syndromes, in which resistance to hormone action is respectively due to mutations in the gene encoding for thyroid hormone receptor TRβ, impaired T4 and T3 transport, and impaired conversion of T4 to T3 mediated by deiodinases. An updated review of each...
متن کاملThyroid hormone resistance.
Thyroid hormone resistance (THR) is a rare syndrome of reduced end organ sensitivity. Patients with THR have elevated serum free thyroxine (FT4), free triiodothyronine (FT3), but normal or slightly elevated serum thyrotropin values. The characteristic clinical feature is goitre without symptoms and metabolic consequences of thyroid hormone excess. THR can be classified on the basis of tissue re...
متن کاملThyroid hormone resistance in identical twins.
A 62 year man with tablet-controlled type 2 diabetes was referred by his general practitioner to the emergency medical unit with shortness of breath. He was found to be in atrial fibrillation with a heart rate of 130 beats/min and the patient was commenced on sotalol and warfarin. Thyroid function tests were requested and found to be abnormal, with thyroid-stimulating hormone (TSH) 7.75 mU/l (r...
متن کاملGrowth and Development in a incidentally diagnosed Resistance to Thyroid Hormone
Resistance to thyroid hormone is an uncommon condition. We report the clinical and laboratory findings of a case with both resistance to thyroid hormone and, a reduced capacity to produce and respond to thyroid hormone. RTH is a disorder characterized by elevated circulating thyroid hormones, state of non-suppressed pituitary TSH secretion and refractoriness to hormone action in peripheral tiss...
متن کاملThyroid hormone and cardiac function in mice deficient in thyroid hormone receptor- or - : an echocardiograph study
Weiss, Roy E., Claudia Korcarz, Olivier Chassande, Kevin Cua, Peter M. Sadow, Eugene Koo, Jacques Samarut, and Roberto Lang. Thyroid hormone and cardiac function in mice deficient in thyroid hormone receptoror : an echocardiograph study. Am J Physiol Endocrinol Metab 283: E428–E435, 2002; 10.1152/ajpendo.00019. 2002.—We investigated the effect of thyroid hormone (TH) receptor (TR) and isoforms ...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2002
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem.87.1.8170